Objective: Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare type of primary liver cancer with characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC).The pathogenesis of cHCCCC is poorly understood due to a shortage of suitable in vitro models.Due to scarce availability of human liver tissue, induced pluripo
Sepsis is a leading cause of morbidity and mortality worldwide.It is defined as the presence of a Systemic Inflammatory Response Syndrome, and it represents a significant burden for the healthcare system.This is particularly true when it is diagnosed in the setting of nosocomial infections, which are usually a matter of concern with regard to medic
The first records of smallpox and rabies date back thousands of years and foot-and-mouth disease in cattle was described in the 16th century.These diseases stood out by their distinct signs, dramatic way of transmission from rabid dogs to humans, and sudden appearance in cattle herds.By contrast, infectious diseases that show variable signs and aff
Identify to be done by using method of lean manufacturing.This research aimed at identify waste and nightstick twm-850xl formulate effort reduction of waste production process smoke in PT.X.The data were collected from manufacturer records, study to determine processing time, as well as interview and quisioners which were distributed to workers in
Several pyrazolo[1,5-a]pyrimidine, triazolo[1,5-a]pyrimidine, pyrido[1,2-a]-benzimidazole, pyrimido[1,2-a]benzimidazole, pyrazolo[5,1-c]triazine, triazolo[5,1-c]-triazine, triazino[4,3-a]benzimidazole and 1,3,4-thiadiazole derivatives were synthesized weboost splitter via the kicker pro comp 10 reactions of (E)-3-oxo-5-phenylpent-4-enenitrile and t